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Sciex

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Sciex

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AB Sciex Switzerland GmbH

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Chromatography and separation (3)

Chromatography HPLC

HPLC separates, identifies, and quantifies chemical substances in liquid samples, including thermally unstable or non-volatile compounds. System selection depends on analyte polarity, molecular size and concentration, required separation efficiency and detection limit, as well as column, mobile phase, and detection type.

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Chromatography LC/MS

LC/MS combines liquid chromatography with mass spectrometry to separate, identify, and quantify components in complex mixtures. It is suited to polar, moderately sized, and thermo- or acid-sensitive molecules. Selection considerations include column separation performance, mass spectrometer type, sensitivity, detection limits, sample complexity, and component compatibility.

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Chromatography UPLC

UPLC separates liquid samples under high pressure using short columns with particles as small as 2 μm. It supports analysis of active substances, impurities and natural products with shorter run times and reduced solvent use. Match column particle size and pressure tolerance to sample requirements for effective resolution.

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Diagnostics (1)

Systems for drug and medication testing

Systems for drug and medication testing screen urine or blood for psychoactive substances and pharmaceutical metabolites in clinical, forensic, and occupational settings. Select according to target substances, sample type, sensitivity, specificity, and qualitative or quantitative needs. Initial immunoassay results may require confirmation by chromatography or mass spectrometry.

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Mass spectrometry (8)

Ion Mobility Mass Spectrometers (IM-MS)

Ion mobility mass spectrometers separate ions by gas-phase mobility as well as mass, improving analysis of complex samples and helping distinguish isobars and structural isomers. Selection should consider the mobility principle, mass resolution and sensitivity, LC/GC compatibility, throughput, and workflow integration.

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MS – Ion trap Mass spectrometry

Ion trap mass spectrometers analyze confined ions to distinguish masses and structures in chemical, environmental, proteomic, research, and quality-control applications. Electromagnetic trapping enables repeated mass selection and excitation for multistage analyses. Select based on trap type, required resolution and sensitivity, sample properties, mass range, and workflow compatibility.

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MS – Mass spectrometer general

Mass spectrometers determine ion mass-to-charge ratios to identify and quantify substances, characterize unknown samples, and support proteomics, metabolomics, process monitoring, and environmental measurements. Selection depends on ion source, analyzer type and resolution, mass range, sensitivity, sample preparation, speed, and chromatography compatibility.

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MS – Quadrupole Mass spectrometer

Quadrupole mass spectrometers measure mass-to-charge ratios for residual gas, trace gas, and complex-mixture analysis in high to ultra-high vacuum. They filter ions using an alternating quadrupole field, balancing accuracy, speed, and ease of use. Select by mass accuracy, sensitivity, dynamic range, ionization method, and sample-preparation compatibility.

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MS – Quadrupole Time of flight Mass spectrometer QTOF MS / HRMR

QTOF MS/HRMS combines quadrupole ion selection with rapid, high-resolution time-of-flight detection for accurate qualitative and quantitative analysis. It supports fragmentation and substance identification in complex samples for pharmaceutical, clinical, forensic, food-safety, and environmental applications. Key selection factors include mass resolution, accuracy, analysis speed, fragmentation flexibility, and software.

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MS – Tandem mass spectrometry MS/MS

Tandem mass spectrometry (MS/MS) selects and fragments specific ions, then analyzes the resulting fragments to support structural elucidation and identification of complex molecules. Used for proteins, peptides, environmental, pharmacological and forensic samples, selection should consider ionization, fragmentation, resolution, sensitivity, mass range, speed and separation compatibility.

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MS – Time of flight Mass spectrometer (TOFMS)

Time-of-flight mass spectrometers determine the mass-to-charge ratios of charged molecules and fragments from ion flight times. They enable rapid qualitative and quantitative analysis in chemistry, biology, environmental analytics, and materials science. Select systems by mass accuracy, resolution, suitable ionization, and coupling options; ion mirrors can improve accuracy and resolution.

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MS – Triple Quad mass spectrometry TQMS

Triple quadrupole mass spectrometry enables targeted monitoring of known molecules through molecular-ion selection, collision-induced fragmentation, and fragment-ion analysis. It supports sensitive, specific measurements in drug metabolism, pharmacokinetics, environmental, and biological studies. Selection should consider detection limits, CID performance, dynamic range, and GC or LC compatibility.

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Molecular biology, PCR and sequencing (2)

Capillary Electrophoresis

Capillary electrophoresis separates charged molecules in narrow capillaries by high-voltage migration through buffered electrolytes. It supports rapid analysis of nanoliter samples for identifying and quantifying ions, peptides, proteins, and nucleic acids. Select systems according to analytes, capillary diameter, detection options, automation, and data-analysis software.

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Electrophoresis sequencer

Electrophoresis sequencers separate DNA samples by gel electrophoresis to generate reproducible band patterns for sequencing and genetic analysis. Choose systems with uniform heating to reduce gel artifacts, convenient gel-sandwich assembly, and suitable gel size or automated run control. They are not intended for protein analysis.

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