Polyclonal antibodies are mixtures of different antibodies obtained from the serum of immunized animals (usually goat, rabbit, mouse or rat). By adsorption to an antigen in an affinity chromatography, all antibodies against the different epitopes of an antigen can be purified together, although the antibodies were produced by different B cells. In contrast, a monoclonal antibody is produced only by clones of a single B cell and is therefore directed only against a single epitope of a protein. Polyclonal antibodies, in contrast to monoclonal antibodies, represent a natural mixture.
The following suppliers offer Antibody polyclonal products.
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