Orbitrap mass spectrometers are high-resolution instruments for mass spectrometry. They use an electrostatic field for precise analysis of mass-to-charge ratios.
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Orbitrap mass spectrometers are used for high-resolution analysis of molecules in research and industry, especially in proteomics, environmental analysis, and material testing. The choice of an Orbitrap MS instrument depends on required resolution, mass range, and compatibility with sample preparation methods. LabFinder supports your search and selection of suitable Orbitrap mass spectrometers with clear categorization and detailed device information.
Orbitrap mass spectrometers are specialized ion trap mass spectrometers used for precise analyses in mass spectrometry. Typical applications include qualitative and quantitative analysis of complex samples, such as in protein research, environmental analysis, as well as material and food testing.
The instrument operates without a magnetic field and instead uses an electrostatic field to generate stable ion orbits, enabling high mass resolution and mass accuracy.
When selecting an Orbitrap mass spectrometer, users should particularly consider the required mass resolution, the mass-to-charge ratio (m/z) of the material to be analyzed, compatibility with existing sample preparation techniques, and the necessary interfaces for data evaluation. The user-friendliness of the software and integration into existing laboratory systems also play a role.
Orbitrap mass spectrometers are characterized by their innovative electrostatic principle, where ions orbit radially around a central electrode and oscillate axially in an ion trap. The oscillation frequency is converted to mass-to-charge ratios via Fourier transformation. This principle covers a broad mass range with high resolution and does not require complex cooling, unlike magnet-based systems such as FT-ICR-MS.
Calibration is performed regularly using standardized reference substances to ensure mass accuracy. Maintenance measures include checking and cleaning the ion optics and detectors, as well as replacing wear parts. The electrostatic design promotes durable and stable performance with manageable maintenance requirements.
Orbitrap mass spectrometers are designed for high-resolution analyses; however, their dynamic measurement range can be limited compared to other MS types. Samples must be ionizable, and appropriate sample preparation methods often require experience for optimal results. The instruments are technically complex and require skilled personnel for operation.
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An Orbitrap mass spectrometer uses an electrostatic field where ions orbit and oscillate around a central electrode. The frequency of this oscillation is converted into mass-to-charge ratios using Fourier transformation.
Orbitrap MS can analyze ionizable samples from fields such as proteomics, environmental analysis, material testing, and food chemistry, with sample preparation methods varying depending on the analysis technique.
Key criteria include the required mass resolution, mass-to-charge ratio range, compatibility with sample preparation, software integration, and ease of operation.
Calibration is performed with reference substances to ensure mass accuracy. Maintenance includes cleaning and checking the ion optics as well as replacing wear parts.
Orbitrap MS require ionizable samples and are technically complex. Their dynamic measurement range may be limited compared to other MS types, and they require trained personnel for operation.
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