Boronic acids are derivatives of boric acid in which one hydroxyl group is substituted by an organyl group. They are therefore organoboron compounds. Furthermore, boronic acids are Lewis acids. A unique feature of boronic acids is that they can form reversible covalent complexes together with saccharides, amino acids and hydroxamic acids. The pKs values of boronic acids are about 9. However, they can also occur in the form of tetrahedral borate complexes whose pKs are ~7. Typical applications for boronic acids are binding to saccharides for fluorescence detection or selective transport across membranes. Boronic acids are used in organic chemistry to link organic substances together using Suzuki coupling. In addition, they are used for transmetallation.
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