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Isolator

Isolators are hermetically sealed enclosures for processing under a controlled atmosphere. They allow gas-tight glove access as well as material transfer via airlock systems.

Product

Isolator

Isolators are hermetically sealed enclosures for processing under a controlled atmosphere. They allow gas-tight glove access as well as material transfer via airlock systems.

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Highlights

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Guide and selection support

Isolators are used for the safe handling of sensitive or hazardous substances in a hermetically sealed working chamber. They allow adjustment of the internal atmosphere, for example with filtered air or inert gas, to protect substances from contamination or undesirable reactions.

When selecting an isolator, leak tightness, glove type, the material of the box, and the method of material transfer play an essential role. Compatibility with the desired atmosphere, as well as size and ergonomics, are also important criteria.

LabFinder offers objective guidance and detailed information on areas of application and selection criteria for isolators, supporting overview and product search tailored to different laboratory requirements.

Applications and Benefits

Isolators provide a hermetically sealed, gas-tight work chamber in which sensitive or hazardous substances can be safely handled. The internal atmosphere is controlled, for example, by filtered air or inert gases, preventing contamination or protecting materials from oxidation.

Gas-tight gloves (often made from butyl rubber) enable manipulation inside the chamber without direct contact. Material transfer is conducted via special airlocks or pass-through chambers, which prevent contamination of the working area.

Selection Criteria

Key factors in selection include the leak tightness and material quality of the enclosure, compatibility with the gases and substances used, as well as comfort and safety during operation. The type and quality of gloves should match the requirements of the work process.

The size of the internal chamber, the number and position of glove ports, and the type of airlocks for material input and output are also important considerations.

Variants and Measurement Principles

Isolators come in various forms depending on the internal atmosphere required. They may operate with filtered air or an inert gas environment.

Construction varies from simple glove boxes to complex systems featuring integrated airlocks, pressure, and gas regulation systems.

Calibration and Maintenance

Regular maintenance is important to ensure the tightness and functionality of gloves, airlocks, seals, and filtration systems. Checking and, if necessary, readjusting the gas atmosphere, as well as cleaning the internal chamber, are typical upkeep requirements.

Limitations of Use

Isolators are limited to handling samples and materials within a defined atmosphere. They do not replace full safety workbenches or cleanroom environments but complement them for specific use cases.

Manipulation is purely manual through gloves, which may affect ergonomic use and handling.

Search Terms and Related Terms

Typical search terms include isolator, glove box, glovebox, gas-tight enclosure, closed atmosphere, butyl gloves, inert gas atmosphere, material transfer airlock, laboratory safety, controlled gas atmosphere, enclosed working chamber, atmosphere-controlled isolator.

Also known as

closed workspace gas-tight isolator glove box glovebox glove chamber inert gas box isolation container laboratory isolator safety isolator sealed work chamber

Frequently asked questions

How does an isolator work in daily laboratory practice?

An isolator provides a hermetically sealed gas chamber where samples can be safely handled under a defined atmosphere via special gloves and airlock systems.

What types of isolators exist in terms of atmosphere?

Isolators can be operated with filtered air or inert gas, with the internal atmosphere tailored to the needs of the specific application.

What should I look for when choosing an isolator?

Key criteria include leak tightness, material quality, glove type and size, ergonomic access, and the kind and size of airlocks for material transfer.

How is material transfer carried out in an isolator?

Material transfer is performed via evacuable airlocks or pass-through chambers, which separate the internal chamber gas-tight from the external environment to prevent contamination.

What are the limitations of using isolators?

Isolators are not suitable for all safety levels and do not replace cleanrooms or safety workbenches. Operation is manual via gloves, which can impact user comfort.

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