MS - Time of flight Mass spectrometer (TOFMS)
Time of flight mass spectrometers (TOFMS) analyze molecules based on their ion flight times. They provide mass spectrometric data with rapid measurement and high mass accuracy.
Product
MS - Time of flight Mass spectrometer (TOFMS)
Time of flight mass spectrometers (TOFMS) analyze molecules based on their ion flight times. They provide mass spectrometric data with rapid measurement and high mass accuracy.
Suppliers
The following suppliers offer MS - Time of flight Mass spectrometer (TOFMS) products.
Suppliers enabled for requests
You can send a request to the suppliers listed above and save time. Describe your requirements and the request will be forwarded to the selected suppliers. They will contact you with suitable proposals without any obligation.
Guide and selection support
Time of flight mass spectrometers (TOFMS) are used in analytical chemistry and molecular analysis to determine the mass of ions by measuring their flight times at defined energy. They are particularly well-suited for rapid and precise determination of mass spectra in research and quality control.
Key selection factors include resolution, sensitivity, and the type of ionization. Devices with integrated ion mirrors improve measurement accuracy by focusing the ion flight path. The analysis mass range and coupling options with other systems are also important criteria.
LabFinder provides guidance and comparison for different TOFMS types in laboratory supply. Users will find product types, technical specifications, and unbiased procurement information free from promotional bias.
Application and Benefits
Time of flight mass spectrometers (TOFMS) are used to determine the masses of charged molecules and fragments, based on their flight time at constant kinetic energy. This method is suitable for qualitative and quantitative molecular analyses in chemistry, biology, environmental analytics, and materials science. Due to rapid measurement and high mass accuracy, TOFMS support applications in research and development processes as well as routine diagnostics.
Selection Criteria
When choosing a time of flight mass spectrometer, mass accuracy and resolution are key factors, as they determine the ability to distinguish between molecular ions. The ionization technique must fit the sample material under investigation. Coupling options with other analytical systems (e.g. chromatography) are also relevant. Devices with ion mirrors enhance accuracy by compensating for differences in ion velocities. Ease of use, data analysis, and maintenance requirements should also be considered.
Variants and Measuring Principles
TOFMS operate on the principle that ions with the same energy are accelerated by an electric field and their flight time to the detector depends on the mass-to-charge ratio. Light ions reach the detector faster than heavier ones. Advanced devices use ion mirrors to extend the flight path and improve ion focusing, which increases mass accuracy and resolution. Variants may differ in detector and ionization technology.
Calibration and Maintenance
Calibration of a TOFMS involves adjusting the flight time-to-mass relationship using reference substances to ensure correct mass values. Regular maintenance ensures stable ion sources, clean flight tubes, and functioning detectors. The intervals for calibration and maintenance depend on usage scope and manufacturer specifications.
Limitations of Application
TOFMS are particularly effective for low to medium mass molecules but may have resolution limitations with very complex mixtures or very large biomolecules. Additionally, sensitivity depends on the ionization technique, which may make some samples harder to analyze. For high-resolution tandem mass spectrometry, more specialized systems are often preferable.
Search Terms and Related Terms
Time of flight mass spectrometer, TOFMS, Time-of-flight MS, TOF MS, Mass spectrometer TOF, MS time of flight, TOF mass spectrometry, Ion spectrometer, Mass spectrum, molecular analysis, mass spectrometric analysis
Also known as
Time of flight mass spectrometry
TOF mass spectrometer
Time-of-flight MS
TOF-MS
TOF MS
Mass spectrometer TOF
TOF mass spectrometry
Time of flight mass spectrometer
Mass spectrometry time of flight
Related categories
Suitable brands
Frequently asked questions
How does a time of flight mass spectrometer (TOFMS) work?
In TOFMS, ions are accelerated to the same kinetic energy and separated in flight according to their mass. Lighter ions reach the detector faster than heavier ones, generating a mass spectrum.
What variants of TOFMS exist and how do they differ?
In addition to standard TOFMS with a direct flight path, many devices utilize ion mirrors to extend the flight path and focus ions. Variants also differ in ionization methods and detectors.
What criteria are important when selecting a TOFMS?
Key criteria include mass accuracy, resolution, available ionization techniques, coupling options with other analytical systems, ease of use, and maintenance requirements.
For which applications are TOFMS particularly suitable?
TOFMS are ideal for rapid, precise analysis of molecular composition in research, environmental analytics, quality control, and biochemistry, especially for low to medium molecular masses.
What are the limitations of time of flight mass spectrometers?
Resolution and sensitivity can be limited with very complex samples or large biomolecules. For high-resolution tandem MS, specialized systems are often better suited.
For suppliers
Register as supplier
Supplier of MS - Time of flight Mass spectrometer (TOFMS)?
Present your company on LabFinder and be listed for this product category as well as suitable related categories and brands.