Sigma-Aldrich
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Sigma-Aldrich
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Featured product categories
Cell Freezing Media
Cell freezing media support long-term cryopreservation by reducing freezing stress and ice-crystal damage, helping preserve cell viability, function, and integrity for later cultivation, analysis, or therapeutic use. Select media based on cell-type compatibility, cryoprotectants, pH and nutrient stability, sterility, and the intended freezing protocol.
View product category →Chemicals – Fluorides
Fluorides are inorganic hydrofluoric acid salts used as fluoride-ion sources in chemical synthesis, materials testing, and analytical procedures. Select by salt type, purity, and physical form—such as powder, granulate, or solution—while ensuring compatibility with reagents and the intended laboratory application.
View product category →Chromatography Thin layer- TLC
Thin-layer chromatography (TLC) separates components in complex samples for rapid mixture analysis, purity checks, identity confirmation, and reaction monitoring. Select plates and development systems based on analyte polarity, required resolution, stationary phase, and detection needs. TLC is primarily suited to qualitative and semi-quantitative analysis.
View product category →CRISPR/Cas Genome Editing
CRISPR/Cas genome editing enables targeted DNA cutting and gene insertion, removal, or modification, including single-nucleotide edits, for genetic-function analysis, model creation, and trait alteration. Select systems by target gene and cell type, Cas nuclease efficiency and specificity, guide RNA quality, and compatibility with experimental requirements.
View product category →Microscope Immersion Oils
Microscope immersion oils improve light-microscopy resolution and clarity by reducing scattering and reflections between the objective and specimen slide. Match the refractive index to the objective lens, and consider viscosity and material compatibility; unsuitable oils or incorrect use can distort images or damage lenses.
View product category →Cell biology and cell culture (4)
Assays Cell Counting
Cell counting assays quantify cells in cultures, blood, or tissue for population characterization, growth monitoring, and sample composition analysis. Methods range from manual microscopy and stains to automated flow cytometry, fluorescence-based, colorimetric, or metabolic assays. Select based on sample type, sensitivity, accuracy, throughput, and detection compatibility.
View product category →Cell Freezing Media
Cell freezing media support long-term cryopreservation by reducing freezing stress and ice-crystal damage, helping preserve cell viability, function, and integrity for later cultivation, analysis, or therapeutic use. Select media based on cell-type compatibility, cryoprotectants, pH and nutrient stability, sterility, and the intended freezing protocol.
View product category →Cells – Competent Cells
Competent cells are pre-treated, usually bacterial cells designed to take up free DNA for transformation, cloning, and genetic manipulation. Choose based on transformation efficiency, host and vector compatibility, and chemical or electroporation-based preparation. They require defined deep-freeze storage and are mainly suited to bacterial hosts.
View product category →Cell Thawing Media
Cell thawing media support gentle reconstitution of cryopreserved cells, helping reduce cold shock and osmotic stress before further culture. Choose formulations according to cell type, composition and compatibility with culture media; protein-free options can help avoid experimental interference. They are not intended for long-term cultivation.
View product category →Chromatography and separation (1)
Chromatography Thin layer- TLC
Thin-layer chromatography (TLC) separates components in complex samples for rapid mixture analysis, purity checks, identity confirmation, and reaction monitoring. Select plates and development systems based on analyte polarity, required resolution, stationary phase, and detection needs. TLC is primarily suited to qualitative and semi-quantitative analysis.
View product category →Laboratory consumables (14)
Chemicals – Aldehydes
Aldehydes are reactive organic chemicals containing the formyl (–CHO) group, used in organic synthesis, polymerization starting materials, and carbonyl-focused analytical procedures. Selection depends on the number of aldehyde groups, chemical stability, purity, and compatibility with reaction conditions; storage should help prevent decomposition or polymerization.
View product category →Chemicals – Amines
Amines are ammonia-derived organic compounds used as reagents and starting materials in synthesis, functional modification, analytical applications, and biochemical processes. Select by primary, secondary, or tertiary structure, aromatic or aliphatic character, purity, storage stability, and compatibility with solvents and reaction conditions to reduce side reactions.
View product category →Chemicals – Biochemicals
Biochemicals are substances such as enzymes, nucleotides and metabolites used in biochemical analyses, enzyme assays and studies of metabolic processes. Select them for their biological function, chemical properties, purity and compatibility with the test system, while considering storage stability and potential reagent incompatibilities.
View product category →Chemicals – Boronic Acids
Boronic acids are boric acid derivatives and Lewis acids used for reversible binding of saccharides, amino acids, and hydroxamic acids, as well as Suzuki coupling and transmetallation. Select structure, substituents, pKa, and complexation ability for compatible targets; binding is pH-sensitive and may be affected by solvents or reactants.
View product category →Chemicals – Bromides
Bromides are halide compounds used in synthesis, analytical procedures, and specialty chemical production as starting materials or catalysts. Choose between inorganic salts and organic bromine compounds based on required reactivity, solubility, purity, physical state, stability, and reagent compatibility.
View product category →Chemicals – Carboxen
Carboxen are spherical synthetic carbon particles used to adsorb volatile organic compounds in sample preparation, analytical procedures, and gas adsorption techniques. Their defined pore structure and hydrophobic surface support kinetic saturation capacity. Select by particle size, pore distribution, surface chemistry, target compatibility, and required adsorption volume.
View product category →Chemicals – Imidazoles
Imidazoles are five-membered, two-nitrogen heterocycles used as organic synthesis starting materials, coordination-chemistry ligands, and building blocks for pharmaceutical or biochemical applications. Their basic and nucleophilic behavior supports diverse reactions. Select derivatives by ring substitution, purity, stability, and compatibility with solvents and reaction conditions.
View product category →Chemicals – Indole and Oxindoles
Indoles and oxindoles are heterocyclic aromatic amines used as building blocks and intermediates in organic synthesis, including active ingredients, functional molecules, and specialty chemicals. Their structures support reactions such as electrophilic aromatic substitution and cyclization. Select by purity, substituents, isomer availability, pathway compatibility, and stability.
View product category →Chemicals – Iodine
Iodine is used in organic and inorganic reactions, analytical detection, microbiological applications, and disinfectant solutions. Choose solid iodine or solutions according to the required concentration, purity, and solvent compatibility: it is sparingly soluble in water but dissolves well in ethanol and aqueous potassium iodide solutions such as Lugol’s solution.
View product category →Chemicals – Nitro Compounds
Nitro compounds are organic molecules containing a nitro group, used in chemical synthesis, materials science, and analytical chemistry. Choose between aliphatic and typically more stable aromatic types based on reactivity and application, while considering purity, reagent compatibility, and sensitivity to heat or light.
View product category →Chemicals – PEG Linkers
PEG linkers are hydrophilic coupling reagents for biochemical and pharmaceutical conjugation, including proteins, peptides, and nucleic acids. Defined chain lengths, molecular weights, and functional end groups enable tuning of solubility, flexibility, and reaction type; selection should match target functional groups and minimize steric hindrance.
View product category →Chemicals – Pyridine
Pyridine is a heterocyclic azine used as a synthesis building block for pharmaceuticals, herbicides, and chemical intermediates, and as a solvent or reagent in laboratory synthesis and analysis. Select grade, purity, delivery form, stability, and reagent compatibility for the intended application.
View product category →Chemicals – Quinoline
Quinoline is an aromatic heterocyclic amine used as a precursor for pharmaceutical actives, dyes, reagents, and other organic compounds, and as a solvent. Selection can consider purity, physical form, solubility, reagent compatibility, stability, and storage requirements.
View product category →Chemicals GENERAL
General chemicals include pure substances and mixtures for research, development, analytics, production, laboratory experiments, and industrial processes. They can function as starting materials, reagents, or auxiliaries. Select by organic or inorganic structure, composition, required purity, compatibility, intended use, and delivery form.
View product category →Diagnostics (1)
Sera
Sera supplement cell culture media with nutrients, growth factors, and lipids to support mammalian cell growth and physiological functions. Selection should consider cell type, medium, source, quality, and experimental needs. Because composition and batches can vary, testing and documentation are important; serum-free alternatives can reduce animal-derived components and variability.
View product category →Microscopy and imaging (1)
Microscope Immersion Oils
Microscope immersion oils improve light-microscopy resolution and clarity by reducing scattering and reflections between the objective and specimen slide. Match the refractive index to the objective lens, and consider viscosity and material compatibility; unsuitable oils or incorrect use can distort images or damage lenses.
View product category →Molecular biology, PCR and sequencing (4)
CRISPR/Cas Genome Editing
CRISPR/Cas genome editing enables targeted DNA cutting and gene insertion, removal, or modification, including single-nucleotide edits, for genetic-function analysis, model creation, and trait alteration. Select systems by target gene and cell type, Cas nuclease efficiency and specificity, guide RNA quality, and compatibility with experimental requirements.
View product category →DNA & RNA Standards
DNA and RNA standards provide defined nucleic acid fragments for estimating sample fragment sizes in gel electrophoresis. Select by required length range, single- or double-stranded format, resolution, and detection-method compatibility. Accuracy depends on gel, staining, marker concentration, and electrophoresis conditions.
View product category →Protein expression system
Protein expression systems produce recombinant proteins by introducing target DNA vectors into cells or cell-free transcription–translation components. They support research, diagnostics, pharmaceutical manufacturing, and enzyme production. Select systems based on protein complexity, required modifications and activity, yield, cultivation effort, and purification needs.
View product category →Protein Standards
Protein standards are reference ladders used in electrophoresis to estimate protein molecular weight and monitor SDS-PAGE or Western blotting. Choose them by required size range, method compatibility, marker visibility, band distribution, and format. They provide migration-based estimates rather than precise protein identification.
View product category →Spectroscopy and analytics (1)
Chemicals – Fluorides
Fluorides are inorganic hydrofluoric acid salts used as fluoride-ion sources in chemical synthesis, materials testing, and analytical procedures. Select by salt type, purity, and physical form—such as powder, granulate, or solution—while ensuring compatibility with reagents and the intended laboratory application.
View product category →All 26 product categories
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